2. Signaling Pathways
  3. Apoptosis
  4. RIP kinase
  5. RIP kinase Isoform
  6. RIP kinase Degrader

RIP kinase Degrader

RIP kinase Degrader (1):

Cat. No. Product Name Effect Purity
  • HY-153598
    LD4172
    		Degrader
    LD4172 is a PROTAC degrader for RIP kinase (RIPK1) with DC50 in nanomolare levels. LD4172 induces apoptosis in cell B16F10 with combination of TNF-α. LD4172 exhibits antitumor efficacy in mouse models. (Pink: ligand for target protein (HY-170613); Black: linker (HY-W012241); Blue: ligand for E3 ligase VHL (HY-112078))